Quick answer
PRP (platelet-rich plasma) treatment for hair loss uses a small amount of your own blood. It's spun to concentrate the platelets and injected into the thinning areas of the scalp, where their growth factors support weakened follicles. It works on follicles that are still alive; it can't grow hair on smooth bald skin.
Quick Numbers
| Source | Your own blood |
|---|---|
| Steps | Draw, spin, inject |
| Session time | About 30–45 minutes |
| Effect lasts | About 18 months on average |
Key Takeaways
| PRP needs living follicles. Smooth bald skin needs a transplant first. |
| Because it's your own blood, there's no risk of allergy or rejection. |
| We apply PRP once at the end of every hair transplant. |
| If regular PRP visits aren't practical, mesotherapy is an easier way to keep supporting the hair. |
PRP (platelet-rich plasma) therapy for hair loss is a three-step medical treatment. A small amount of blood is drawn from your arm, spun in a centrifuge to separate a plasma layer rich in platelets, and that concentrate is injected into the scalp. The whole visit usually takes 30 to 45 minutes, and you can go back to normal life the same day.
This page explains what PRP can and can't do for thinning hair, how a session works, how long the results last and how we use PRP alongside a hair transplant at our clinic in Istanbul.
What is PRP hair treatment?
Platelets are small blood cells best known for helping blood clot. They also carry growth factors, signalling proteins that the body uses to repair tissue. That's why platelet concentrates have been used for many years to help slow-healing wounds.
In hair treatment, the idea is to bring a high concentration of those growth factors to the follicles. Follicles affected by pattern hair loss gradually shrink and produce thinner, shorter hairs. PRP aims to support those weakened follicles so that the hair they produce stays thicker and the shedding slows down.
Because the plasma comes from your own blood, nothing foreign is injected. That's the main reason PRP is so well tolerated.
Does PRP actually regrow hair?
PRP works on follicles that are still alive, even if they're weak or resting. It can thicken thinning hair and slow down shedding. It can't grow hair from nothing. If an area has been smooth and bald for years, the follicles there are gone, and no injection will bring them back. In that case the area first needs new follicles from a hair transplant, and PRP can then support the result.
Results also differ from person to person. Patients in the early stages of thinning, with plenty of miniaturized hair still present, usually see the clearest benefit. Research reviews generally report improved hair density and thickness after a series of sessions, although protocols vary between clinics.
Dr. Caymaz Insight
| I use PRP as a supporting tool, after a transplant or when thinning has just started. I don't offer it as a replacement for surgery on a scalp that's already smooth. Platelets improve the environment around a follicle; they don't create new ones. When I explain it that way, patients make better decisions and nobody is disappointed. |
How is PRP prepared and applied?
- Blood draw. A small tube of blood is taken from the arm, much like a routine blood test.
- Centrifuge. The tube is spun for several minutes. The red cells settle at the bottom, and the platelet-rich plasma is collected from the top.
- Application. The plasma is injected with a very fine needle into the thinning areas of the scalp. A session usually ends within 30 to 45 minutes.
Most patients describe the injections as a quick pinching feeling. You can wash your hair and go back to work the next day.
Does PRP have side effects?
PRP is made from your own blood, so there's no risk of an allergic reaction or rejection, and it has no known side effects. Some patients notice light tenderness at the injection points for a few hours, which settles on its own. It's suitable for both men and women, and it can be combined with medical treatment for hair loss.
How many sessions do you need, and how long does it last?
PRP works best as a series rather than a single visit. For thicker hair, a common schedule is a session at months 1, 3, 4, 6, 9 and 12 over the first year. If you’d like more frequent sessions, having PRP every month is also fine and does no harm. The results aren't permanent, but they last about 18 months on average, and up to 2 years has been reported. After the first year, many patients keep the effect with one maintenance session a year.
Your exact plan depends on how advanced the thinning is and what other treatment you're using, so it's set after an examination.
PRP in the hair transplant process
At our clinic, every hair transplant ends with one PRP application on the day of surgery. Because the newly implanted follicles sit in fresh channels, the plasma can be applied directly onto the scalp without extra injections. It's included in the operation day and supports early healing of the recipient and donor areas.
After the transplant, PRP sessions in the following months can help the new and existing hair grow thicker. They're optional. The transplanted follicles grow without them, and the decision depends on your hair and your schedule.
Is mesotherapy an easier alternative?
Regular PRP visits aren't practical for everyone, especially for patients who live abroad and return home after surgery. For them, hair mesotherapy can be an easier way to keep supporting the scalp. Mesotherapy delivers vitamins, minerals and amino acids to the scalp, and the application is simpler than PRP because no blood needs to be drawn or processed.
We mention it as an option, not a requirement. Neither PRP nor mesotherapy is necessary for a transplant to succeed, and we'll tell you honestly whether either one is worth it in your case.
| Scenario | Typical role |
|---|---|
| Early thinning | Can thicken weak hair, often with medical treatment |
| Day of transplant | One application at the end of surgery |
| After a transplant | Optional sessions to support thicker growth |
| Smooth bald scalp | Transplant needed first |
Sources & clinical references
No. PRP works on follicles that are still alive. Smooth bald skin has lost its follicles and needs a hair transplant first.
A small amount of blood is drawn, spun in a centrifuge to concentrate the platelets, then injected into the thinning areas of the scalp. A session takes about 30 to 45 minutes.
PRP is made from your own blood, so there's no risk of allergy or rejection, and it has no known side effects. Light tenderness at the injection points can last a few hours.
A common first-year schedule is months 1, 3, 4, 6, 9 and 12. If you’d like more frequent sessions, having PRP every month is also fine and does no harm. The effect lasts about 18 months on average, and many patients continue with one session a year.
Yes. We apply PRP once at the end of every transplant. Sessions in the following months are optional and can help the hair grow thicker.
It can be. Mesotherapy is easier to apply because no blood needs to be drawn, which makes it practical for patients who can't come for regular PRP sessions. Neither is required for a transplant to succeed.
No. PRP can be used alongside medical treatment, but decisions about medication need a physician's assessment.
Hair Loss — Frequently Asked Questions
Expert Answers by Dr. Erkam Caymaz, Istanbul
